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黃羿,任敏,錢波,黃齡,楊青,李媛,張耀,印小天,丁嘉麗,鄭家彬,王思懿,吳剛,楊童舒,李菲兒,黃日瑩,楊昆,董思成,左葉,此沙
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李知恩,邊佑錫,魯常泫,孔升延,劉秀彬,李妍,李才元,蔡書安,樸俊勉
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更新第40集
任嘉倫,王鶴潤,張凱瑩,王以綸,黃羿,付偉倫,孫澤源,張禕格,宋文作,劉尚麟,劉學義,鄭業成,彭禺厶,黃毅,高曙光,成泰燊,呂行,肖順堯,丁笑瀅,李康,王名揚,宮正曄,梁詠妮,張芷溪,加奈那,陳欣予,王子睿,邱心志,何中華,盧勇
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第40集已完結
田曦薇,張凌赫,任豪,孔雪兒,鄧凱,李卿,喻鍾黎,劉琳,嚴屹寬,嶽暘,杜淳,譚凱,毛林林,葉祖新,於洋,李建義,田麗,寇佔文,付淼,盧勇,苑冉,王九勝,高卿塵,賈妮,金珈,林沐然,林思意,何昶希,高上淇,李殿尊,管雲鵬,管梓淨,張舒淪,李昱唯,向夏,韓浩天,王亭文,曹晏寧,吳佳峻,楊賀文
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全38集
鍾漢良,朱珠,李夢,經超,任彬,徐海喬,郭曉婷,高卿塵,海陸,那家威,程一丹
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田中真弓,中井和哉
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第8集完結
樸恩斌,車銀優,金海淑,孫賢周,林成宰,崔大勳,裴奈拏
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全37集
王姬,楊採鈺,何藍逗,倪虹潔,李殿尊,馮紹峯,曹可凡,張超,晏紫東,唐嫣,吳玉芳,陳昊森,趙又廷,劉恩佳,沙寶亮,楊晨,柳珊,鮑大志,杜雙宇,周野芒,劉鈞,王菊,吳施樂,王藝荻,陳國慶
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林智妍,許南俊,張勝祖,李世熙,金玟錫,蔡書安,金海淑,尹周相,尹炳熙,鄭英珠,白恩惠,白智媛,樸鎮宇,吳敏愛,張河恩
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全24集
王傳君,王驍,王沛祿,朱雲峯,欒元暉,譚希和,王正權,梅寶萊,田曦薇,姜冠南,張瑞涵,榮飛,宗俊濤,董寶石,宋鬱河
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張若瑜,李欣,程玉珠,杜晴晴,虞曉旭,於凱隆,高嗣航,張恆,王宇航,劉宇軒,唐昊
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王麗坤,張嘉益,苗阜,秦海璐,劉浩存,竇驍,張國強,姬他,王曉晨,孫浩,李澤鋒,扈耀之,王海燕,石文中,翟子路,韓沛穎
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第6集
劉濤,楊紫,韓東君,李春嬡,徐百慧,周知,曹磊,王文綺,楊斯,田小潔,李泓良,李洪濤,付嘉,吳冕,李寶安,富大龍,張喜前,洪洋,朱輝,劉凱,張渟渟,王玉寧,王梓豪,王學東,謝心,娜菲莎
In 2261, the Vorlons join the Shadow War, but their tactics become a concern for the alliance when the Vorlons begin destroying entire planets which they deem to have been "influenced" by the Shadows. Disturbed by this turn of events, Babylon 5 recruits several other powerful and ancient races (the First Ones) to their cause, against both the Shadows and the Vorlons. Captain John Sheridan returns to the station after escaping from Z'ha'dum, but at a price: barring illness or injury, he has only 20 years left to live. He is accompanied by a mysterious alien named Lorien who claims to be the oldest sentient being in the galaxy.
Hours before Sheridan's return, Garibaldi is rescued and returned to the station, in rather dubious circumstances. He is markedly more paranoid and suspicious of other alien races and of Sheridan than he was before.
Centauri Emperor Cartagia forges a relationship with the Shadows. Londo Mollari engineers the assassination of Cartagia and repudiates his agreement with the Shadows. Londo kills Mr. Morden and destroys the Shadow vessels based on the Centauri homeworld, in an attempt to save his planet from destruction by the Vorlons. Aided by the other ancient races, and several younger ones, Sheridan lures both the Vorlons and the Shadows into an immense battle, during which the Vorlons and Shadows reveal that they have been left as guardians of the younger races, but due to philosophical differences, ended up using them as pawns in their endless wars throughout the ages. The younger races reject their continued interference, and the Vorlons and Shadows, along with the remaining First Ones, agree to depart the galaxy forever.
After the Shadows are defeated Garibaldi leaves his post as security chief and works on his own as a "provider of information". He begins working for one William Edgars, a Mars Tycoon, who is married to Garibaldi's former love. While he works ever closer with Edgars, he becomes increasingly aggressive towards Sheridan and eventually leaves Babylon 5.
Minbar is gripped by a brief civil war between the Warrior and Religious castes. Delenn secretly meets with Neroon of the Warrior caste and convinces him that neither side can be allowed to win. She tells him that she will undergo a ritual wherein she will be willing to sacrifice herself, but will stop the ritual before she actually dies. When Neroon sees that she actually intends to go through the entire ritual, he rescues her and sacrifices himself instead, declaring that, although he was born Warrior, in his heart he is Religious.
As part of the ongoing conflict between Earth and Babylon 5, Garibaldi eventually betrays Sheridan and arranges his capture in order to gain Edgars' trust and learn his plans. Garibaldi later learns that Edgars created a virus that is dangerous to only telepaths. It is then revealed, that Garibaldi was actually abducted by the Psi-Corps at the end of Season 3 and re-programmed by Bester to provide information to him at the right time. Bester releases Garibaldi of his programming, and allows him to remember everything he has done since being kidnapped. Edgars is killed and his wife disappears, but is reunited with Garibaldi after the end of the war. Garibaldi helps free Sheridan and return him to the campaign to free Earth. An alliance led by Babylon 5 frees Earth from totalitarian rule by President Clark in a short but bloody war. This culminates in Clark's suicide and the restoration of democratic government. Mars is granted full independence, and Sheridan agrees to resign his commission. The League of Non-Aligned Worlds is dissolved and reformed into the Interstellar Alliance, with Sheridan elected as its first President and continuing his command of the Rangers, who are to act as a galactic equivalent of United Nations peacekeepers.
In the season finale, the events of 100, 500, 1000, and one million years into the future are shown, depicting Babylon 5's lasting influence throughout history. Amongst the events shown are the political aftermath of the 2261 civil war, a subsequent nuclear war on Earth involving a new totalitarian government in the year AD 2762, the resulting fall of Earth into a pre-industrial society, the loss and restoration of humanity's knowledge of space travel, and the final evolution of mankind into energy beings similar to the Vorlons, after which Earth's sun goes nova.